Photo RappBastian E. Rapp, Prof. Dr.-Ing.

Chair, Laboratory of Process Technology | NeptunLab

Department of Microsystems Engineering (IMTEK)
Albert-Ludwigs University of Freiburg
Georges-Köhler-Allee 103 | 79110 Freiburg im Breisgau | Germany

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Curriculum Vitae

Key Figures

  • High-impact publications, among others in Nature, Science, Nature Communications, Advanced Materials, Angewandte Chemie: 49 original research papers, 8 reviews,
    2 books, 4 book chapters, more than 2800 citations
  • ERC Consolidator Grant (2019 – 2024)
  • 11 patents granted, 26 patents in revision
  • More than 10.800.000€ acquired third party funding from all relevant funding sources
  • More than 6.000.000 € acquired in entrepreneurial activity
  • Features in public media including BBC, New York Times, Discovery Channel, Deutschlandfunk, Focus; more than additional international media outlets (full list: www.neptunlab.org/in-the-media)
  • 95 contributions to international peer-reviewed conferences
  • 86 invited talks in academia and industry including several keynotes

Key Publications

  • M. Mader, O. Schlatter, B. Heck, A. Warmbold, A. Dorn, H. Zappe, P. Risch, D. Helmer, F. Kotz, F, B. E. Rapp, Science, 2021 (accepted).
  • D. Helmer, B. E. Rapp: "Divide and print", Nature Materials (impact factor: 38.9), 19, 131–133, 2020.
  • F. Kotz, P. Risch, K. Arnold, A. Quick, M. Thiel, A. Hrynevich, P. D. Dalton, D. Helmer, B. E.  Rapp: "Fabrication of arbitrary three-dimensional suspended hollow microstructures in transparent fused silica glass", Nature Communications (impact factor: 12.4), 10, 1, 14939, 2019.
  • F. Kotz, B. E. Rapp: "Glassomer - Processing fused silica glass like a polymer", Advanced Materials (impact factor: 19.79), 30, 1707100, 2018, (cover page).
  • F. Kotz, K. Arnold, W. Bauer, D. Schild, N. Keller, K. Sachsenheimer, T. M. Nargang, C. Richter, D. Helmer, B. E. Rapp: "Three-dimensional Printing of Transparent Fused Silica Glass", Nature, 544, 337-339, 2017.
  • D. Helmer, N. Keller, Frederik Kotz, F. Stolz, C. Greiner, T. M. Nargang, K. Sachsenheimer, B. E. Rapp: "Transparent, abrasion-insensitive superhydrophobic coatings for real-world applications", Scientific Reports (impact factor: 4.8), 7, 1, 15078, 2017.
  • D. Helmer, A. Voigt, S. Wagner, N. Keller, K. Sachsenheimer, F. Kotz, T. M. Nargang, B. E. Rapp: "Suspended Liquid Subtractive Lithography: One-step generation of 3D channel geometries in viscous curable polymer matrices", Scientific Reports (impact factor: 4.8), 7, 1, 7387, 2017.
  • F. Kotz, K. Plewa, W. Bauer, N. Schneider, N. Keller, T. Nargang, D. Helmer, K. Sachsenheimer, M. Schäfer, M. Worgull, C. Greiner, C. Richter, B. E. Rapp: "Liquid Glass: A Facile Soft Replication Method for Structuring Glass", Advanced Materials, 28, 23, 4646, 2016. Featured: "Optical fabrication: Liquid glass", Nature Photonics 10, 440, 2016.

Professional experience

  • since 05/2020: Managing Director of Freiburg Material Research Center (FMF)
  • since 02/2020: Cospeaker of ZEISS Research Cluster Interactive and Programmable Materials (IPROM)
  • since 2019: Full member of Freiburg Material Research Center (FMF), Member of Freiburg Center for Interactive Materials and Bioinspired Technologies (FIT), Member of DFG Excellence Cluster Living, Adaptive and Energy-autonomous Materials Systems (livMatS)
  • since 05/2019: ERC Consolidator Grantee for a project on the development of tactile displays for the visually impaired
  • since 2018: Full Professor (W3 tenured), Laboratory of Process Technology,  University of Freiburg, Department of Microsystems Engineering (IMTEK)
  • since 04/2018: Co-Founder, Founding Chief Executive Officer (CEO) and current Chief Technical Officer (CTO) of Glassomer GmbH
  • 06/2017: Habilitation, Microfluidics: Mechanics, Modeling and Mathematics, 830 pages, Elsevier Scientific Publishing, ISBN 9781455731411
  • 2014 – 2021: Head of BMBF Young Investigator Group Fluoropor, IMT/KIT
  • 2009 – 2014: Head of Young Investigator group "Indirect microfluidic systems", IMT/KIT
  • since 2008: Principal Investigator and Postdoc, IMT/KIT, non-tenured
  • 2005 – 2008: PhD thesis (Dr.-Ing., "summa cum laude", final grade: 1.0+, mechanical engineering), Development of a surface acoustic wave based biosensor array system with disposable indirect microfluidics, Prof. Volker Saile (University of Karlsruhe) / Prof. Andreas Manz (KIST Europe)
  • 2005 – 2007: Studies in applied cultural sciences (Centre for Cultural and General Studies ZAK, KIT), final grade: 1.2
  • 2000 – 2005: Studies in mechanical engineering (University of Karlsruhe), final grade: 1.2

Distinctions

  • 2021 Nominated by German Minister of Research and Education Anja Karliczek for the Deutscher Zukunftspreis (engl. German Future Prize) of the German President
  • 2014 Elected Emerging Investigator by Lab-on-a-Chip (Royal Society of Chemistry) the most important journal in the field of microfluidics and miniaturization

Scientific awards, prizes and fellowships

  • 2019 Technology Transfer Prize for Glassomer GmbH, KIT, Karlsruhe
  • 2019 Start-Up Award Rapid Tec for Glassomer GmbH
  • 2019 Freiburger Innovation Award for Glassomer GmbH
  • 2019 Start-Up Award of Formnext for Glassomer GmbH
  • 2019 2nd place Start-Up-BW finals for Glassomer GmbH, Stuttgart
  • 2018 Winner of the Start-Up BW Founding Award, Konstanz
  • 2018 Materialica Design + Technology Gold Award 2018 of EMove360° for the Glassomer technology
  • 2018 GMM-Prize of the Gesellschaft Mikroelektronik, Mikrosystem- und Feinwerktechnik (GMM, translated: Association of Microelectronic, Microsystems and Precision Engineering) of the Verband der Elektrotechnik, Elektronik und Informationstechnik (VDE, translated: Association of Electrical Engineering, Electronics and Information Technology) for the work on 3D printing of glass
  • 2015: GMM award of the VDE (Verband der Elektrotechnik, Elektronik und Informationstechnik)
  • 2014: Successful application for a BMBF Research Group (NanoMatFutur)
  • 2014: Elected Emerging Investigator by Lab-on-a-Chip (Royal Society of Chemistry)
  • 2011: Winner of BMBF-Workshop Systeme für den Menschen
  • 2009: Prize Südwestmetallförderpreis 2009, Employers Federation Südwestmetall
  • 2008 – 2010: Research Fellowship Max-Buchner-Forschungsstiftung, DECHEMA Gesellschaft für Chemische Technik und Biotechnologie e.V., (MBFSt #2676)
  • 2006: Prize REHAU-Preis Technik 2006, REHAU AG+Co
  • 2005: Prize Edison Award 2005, General Electric Foundation and Institute of International Education
  • 2003 – 2005: Fellowship Research and Technology, DaimlerChrysler AG

Entrepreneurship

  • 2021: 2.500.000 € Grant + 3.500.000 € Equity awarded for Glassomer GmbH following a successful application to the Blended Finance Accelerator Program of the European Innovation Council (EIC)
  • Since 2018: Co-Founder, Founding Chief Executive Officer (CTO) and current Chief Technical Officer (CTO) of Glassomer GmbH

Supervised students’ awards and prizes (selection)

  • Gips-Schüle Young Investigator Award for PhD student Frederik Kotz, 2020
  • Deutscher Studienpreis of the Körber Foundation for PhD student Frederik Kotz, 2019.
  • Prize Südwestmetallförderpreis of the Verband der Metall- und Elektroindustrie Baden-Württemberg for PhD student Frederik Kotz, 2019.
  • KIT PhD award for PhD student Frederik Kotz, 2019.
  • Technology Review’s Innovatoren unter 35 Award (translated: Innovators younger than 35) for PhD student Frederik Kotz, 2018 (German winner), 2019 (European winner).
  • Paul Wurth Award 2017 for PhD student Patrick Risch, 2017.
  • Deutscher Studienpreis of the Körber Foundation for PhD student Elisabeth Wilhelm, 2016.

Press and media coverage

Features in public media including BBC, New York Times, Discovery Channel, Deutschlandfunk, Focus and more than 400 additional international media outlets.

For a full list of media coverage on Bastian E. Rapp and the NeptunLab see the In the media section.

Short Biography

Prof. Dr.-Ing. Bastian E. Rapp is the Full Professor of Process Technology at the Department of Microsystems Engineering (IMTE) and head of the NeptunLab. He is the Managing Director of the Freiburg Material Research Center (FMF). He is cofounder, founding CEO and current CTO of the spin-off Glassomer GmbH which commercializes next-generation 3D printing processes for glass.

For his work he was awarded, among others, the Edison Prize of the General Electric (GE) Foundation, the REHAU award, the GMM award, and the Südwestmetallförderpreis. In 2019 he received an ERC Consolidator Grant from the European Research Council for his work on tactile displays for the visually impaired. His work has been published in the most important international journals including Lab-on-a-Chip, Advanced Materials, Angewandte Chemie and Nature and has been featured in national and international radio and print media including the BBC, the New York Times and the Discovery Channel. In 2021 he was nominated by German Minister of Research and Education Anja Karliczek for the German Future Award of the German President for Technology and Innovation.

Bastian Rapp studied mechanical engineering at the University of Karlsruhe and finished his PhD at the same university in 2008 working on biosensors for biomedical diagnostics. In 2017 he finished his Habilitation at the Karlsruhe Institute of Technology with the publication of a textbook on fluid dynamics in microfluidics.

His research focuses on the development of novel materials, processes and applications in microsystem engineering, life sciences and biotechnology as well as instrumental and clinical analytics.

 

Publications

Journal Papers

S. Bhagwat, L. Hambitzer, R. Prediger, P. Zhu, A. Hamza, S.K. Kilian, S. Kluck, P. Pezeshkpour, F. Kotz-Helmer. B.E. Rapp, Tungsten Oxide Coated Liquid Metal Electrodes via Galvanic Replacement as Heavy Metal Ion Sensors, Sensors, 2024, 24(2), 416 | Link

D. Böcherer, Y. Li, S. Kluck, N. Nekoonam, P. Zhu, B. E. Rapp, F. Kotz-Helmer, D. Helmer, COLOR3D – Multicolored 3D printing of wood composites by submicron structuring, Addit. Manuf., 2023, 75, 103723 l Link

S. Bhagwat, A. Goralczyk, M. Luitz, L. Sharieff, S. Kluck, A. Hamza, N. Nekoonam, F. Kotz-Helmer, P. Pezeshkpour, and B. E. Rapp, In Situ Actuators with Gallium Liquid Metal Alloys and Polypyrrole-Coated Electrodes, ACS Appl. Mater. Interfaces, 2023, 15, 7, 10109-10122 | Link

 

F. Mayoussi, A. Usama, N. Nekoonam, I. Knauer, D. Böcherer, B. E. Rapp, D. Helmer, Influence of Parylene F Coatings on the Wetting Properties of Soft Polydimethylsiloxane (PDMS), Materials, 2023, 16(5), 1938Link

F. Mayoussi, A. Usama, K. Karimi, N. Nekoonam, A. Goralczyk, P. Zhu, D. Helmer, B. E. Rapp, Superrepellent Porous Polymer Surfaces by Replication from Wrinkled Polydimethylsiloxane/Parylene F, Materials, 2022, 15(22), 7903 | Link

A. Goralczyk, S. Savicheva, R. Montazeri, S. Fine , F. Mayoussi, P. Zhu,, K. Steffen, F. Kotz-Helmer, D. Helmer, B. E. Rapp, Spray-Coating of Superhydrophobic Coatings for Advanced Applications, Adv. Eng. Mater, 2022, 2201314 | Link

Mader, M., Prediger, R., Schell, K. G., Schmidt, G., Dorn, A., Jenne, S., Kluck, S., Hambitzer, L., Luitz, M., Schwarz, C., Milich, M., Greiner, C., Rapp, B. E., Kotz-Helmer, F., Injection Molding of Magnesium Aluminate Spinel Nanocomposites for High-Throughput Manufacturing of Transparent Ceramics. Adv. Sci. 2022, 2204385. | Link

F. Mayoussi, Y. Chen, D. Mössner, S. Franco Corredor, A. Goralczyk, M. Mader, A. Warmbold, F. Kotz-Helmer, D. Helmer ,B. E. Rapp, Smooth Transparent Omniphobic Coatings with Remarkable Liquid Repellence, Adv. Mater. Interfaces, 2022, 2201080| Link

Kluck, S., Hambitzer, L., Luitz, M. et al. Replicative manufacturing of metal moulds for low surface roughness polymer replication. Nat Commun 13, 5048 (2022). Link

P. Pezeshkpour, K. Sachsenheimer, A. Goralczyk, F. Mayoussi, M. Mader, F. Kotz-Helmer, D. Helmer, B. E. Rapp, A Real-Time Capacitive Sensor to Detect the Stability of Salvinia Layers on Porous Superhydrophobic Polymers Under Shear, Adv. Mater. Technol., 2022, 2200287 | Link

A. Goralczyk, S. Bhagwat, F. Mayoussi, N. Nekoonam, K. Sachsenheimer, P. Hou, F. Kotz-Helmer, D. Helmer, B. E. Rapp, Application of Micro/Nanoporous Fluoropolymers with Reduced Bioadhesion in Digital Microfluidics, Nanomaterials, 2022, 12(13), 2201 | Link

A. Goralczyk, F. Mayoussi,  M. Sanjaya, S. Franco Corredor, S. Bhagwat, Q. Song, S. Schwenteck, A. Warmbold, P. Pezeshkpour, B. E. Rapp, On-Chip Chemical Synthesis Using One-Step 3D Printed Polyperfluoropolyether, Chem Ing Tech (Weinh), 2022, 94, No. 7, 1–9 | Link

J. T. Toombs, M. Luitz, C. C. Cook, S. Jenne, C. C. Li, B. E. Rapp, F. Kotz-Helmer, H. K. Taylor, Volumetric additive manufacturing of silica glass with microscale computed axial lithography Science 2022, 376, 6590, 308 | Link

S. Franco Corredor, F. Mayoussi, M. Luitz, A. Kick, A. Goralczyk, D. Böcherer, G. Vera, D. Helmer, F. Kotz-Helmer, B. E. Rapp, A Polystyrene Photoresin for Direct Lithography of Microfluidic Chips. Adv. Mater. Technol. 2022, 2200084 | Link

S. Bhagwat, C.O'Brien, A. Hamza, S. Sharma, C. Rein, M. Sanjaya, D. Helmer, F. Kotz-Helmer, P. Pezeshkpour, B.E.Rapp, An On-Chip Liquid Metal Plug Generator, Adv. Mater. 2022, 2201469 | Link

A. Goralczyk, M. Zhu, F. Mayoussi, M. Lallemang, M. Tschaikowsky, A. Warmbold, S. Caliaro, F. Tauber, B. N. Balzer, F. Kotz-Helmer, D. Helmer, B. E. Rapp, Study of repellence on polymeric surfaces with two individually adjustable pore hierarchies. Chem. Eng. J. 2022, 437, 135287 | Link

A. Sherbaz, B. M. K. Konak, P. Pezeshkpour, B. Di Ventura, Bastian E. Rapp, Deterministic Lateral Displacement Microfluidic Chip for Minicell Purification, Micromachines, 2022, 13, 365 |Link

 

M. Mader, L. Hambitzer, P. Schlautmann, S. Jenne, C. Greiner, F. Hirth, D. Helmer, F. Kotz-Helmer, B.E. Rapp: "Melt-Extrusion-Based Additive Manufacturing of Transparent Fused Silica Glass", Adv. Sci., 2021, 8, 2103180 | Link

M. Mader, C. Rein, E. Konrat, S.L. Meermeyer, C. Lee-Thedieck, F. Kotz-Helmer, B.E. Rapp: "Fused Deposition Modeling of Microfluidic Chips in Transparent Polystyrene", Micromachines, 2021, 12(11), 1348 | Link

F. Mayoussi, E. H. Doeven, A. Kick, A. Goralczyk, Y. Thomann, P. Risch, R. M. Guijt, F. Kotz, D. Helmer, B. E. Rapp: "Facile fabrication of micro-/nanostructured, superhydrophobic membranes with adjustable porosity by 3D printing", Journal of Materials Chemistry A, 2021 | Link

Luitz, M., Lunzer, M., Goralczyk, A., Mader, M., Bhagwat, S., Warmbold, A., Helmer, D., Kotz, F., Rapp, B. E., High Resolution Patterning of an Organic–Inorganic Photoresin for the Fabrication of Platinum Microstructures. Adv. Mater. 2021, 33, 2101992 | Link

M. Mader, O. Schlatter, B. Heck, A. Warmbold, A. Dorn, H. Zappe, P. Risch, D. Helmer, F. Kotz, B. E. Rapp: “High-throughput injection molding of transparent fused silica glass”, Science, 2021 | Link

F. Kotz, A. S. Quick, P. Risch, T. Martin, T. Hoose, M. Thiel, D. Helmer, B. E. Rapp: “Two‐Photon Polymerization of Nanocomposites for the Fabrication of Transparent Fused Silica Glass Microstructures”, Advanced Materials, 33, 9, 2006341, 2021 | Link

F. Kotz, M. Mader, N. Dellen, P. Risch, A. Kick, D. Helmer, B. E. Rapp: “Fused deposition modeling of microfluidic chips in polymethylmethacrylate”, Micromachines, 11(9), 873, 2020. | Link

D. Helmer, B. E. Rapp: "Divide and Print", Nature Materials, 19, 131-133, 2020 | Link

M. Langenhorst, D. Ritzer, F. Kotz, P. Risch, S. Dottermusch, A. Roslizar, R. Schmager, B. S. Richards, B. E. Rapp, U. W. Paetzold: "Liquid Glass for photovoltaics: multi-functional front cover glass for solar modules", ACS Materials & Interfaces, 2019 | Link

K. Sachsenheimer, C. Richter, D. Helmer, F. Kotz, B. E. Rapp: "A Nontoxic Battery with 3D-printed housing for on-demand operation of microcontrollers in microfluidic sensors", Micromachines, 10, 599, 2019 | Link
 

P. Risch, D. Helmer, F. Kotz, B. E. Rapp: "Analytical solution of the time-dependent microfluidic poiseuille flow in rectangular channel cross-sections and its numerical implementation in Microsoft Excel", Biosensors, 9(2), 67, 2019, |Link|

F. Kotz, P. Risch, K. Arnold, S. Sevim, J. Puigmarti-Luis, A. Quick, M. Thiel, A. Hrynevich, P. Dalton, D. Helmer, B. E. Rapp: “Fabrication of arbitrary three-dimensional suspended hollow microstructures in transparent fused silica glass”, Nature Communication, 10, 1439, 2019 | Link

N. Keller, J. Bruchmann, T. Sollich, C. Richter, R. Thelen, F. Kotz, T. Schwartz, D. Helmer, B. E. Rapp: "Study of Biofilm Growth on Slippery Liquid-Infused Porous Surfaces Made from Fluoropor", ACS Applied Materials & Interfaces, 11, 4480-4487, 2019 | Link

U. Stahl, A. Voigt, M. Dirschka, N. Barié, C. Richter, A. Waldbaur, F. J. Gruhl, B. E. Rapp, M. Rapp, K. Länge: "Long-term capability of polymer-coated surface transverse wave sensors for distinguishing vapors of similar hydrocarbons", Sensors & Actuators: B. Chemical, 274, 560–564, 2018 | Link.

AY010033 IFC PUBLICITY

T. M. Nargang,  R. Dierkes,  J. Bruchmann,  N. Keller,  K. Sachsenheimer,  C. Lee-Thedieck,  F. Kotz,  D. Helmer  and B. E. Rapp: "Photolithographic structuring of soft, extremely foldable and autoclavable hydrophobic barriers in paper", Analytical Methods, 10, 4028-4035, 2018 | Link

Cover1F. Kotz, N. Schneider, A. Striegel, A. Wolfschläger, N. Keller, M. Worgull, W. Bauer, D. Schild, M. Milich, C. Greiner, D. Helmer, B. E. Rapp: “Glassomer: Processing Fused Silica Glass like a Polymer”, Advanced Materials, 30, 1707100, 2018 CoverLink

F. Kotz, P. Risch, D. Helmer, B. E. Rapp: “Highly Fluorinated Methacrylates for Optical 3D Printing of Microfluidic Devices”, Micromachines, 9, 3, 15, 2018 (invited) | Link

V. Kappings, C. Grün, D. Ivannikov, I. Hebeiss, S. Kattge, I. Wendland, B. E. Rapp, M. Hettel, O. Deutschmann, U. Schepers: "vasQchip: A novel microfluidic artificial blood vessel scaffold for vascularized 3D tissues", Advanced Materials Technologies (impact factor: to be announced), 3, 1700246, 2018| Link

C. Richter, S. Schneider, B. E. Rapp, S. Schmidt, M. Schüßler, R. Jakoby, J. Bruchmann, M. Bischer, T. Schwartz: "Towards Biofilm Spectroscopy – A Novel Microfluidic Approach for Characterizing Biofilm Subpopulation by Microwave-Based Electrical Impedance Spectroscopy", Frequenz, 72, 3, 123-134, 2018 (invited).

D. Helmer, N. Keller, F. Kotz, F. Stolz, C. Greiner, T. M. Nargang, K. Sachsenheimer, B. E. Rapp: „Transparent, abrasion-insensitive superhydrophobic coatings for real-world applications”, Nature Scientific Reports, 7, 1, 15078 | Link

Cover2F. Kotz, K. Arnold, S. Wagner, W. Bauer, N. Keller, T. M. Nargang, D. Helmer, B. E. Rapp: "Liquid PMMA: A High Resolution Polymethylmethacrylate Negative Photoresist as Enabling Material for Direct Printing of Microfluidic Chips", Advanced Engineering Materials, 20, 1700699, 2017 |Back Cover | Link

D. Helmer, A. Voigt, S. Wagner, N. Keller, K. Sachsenheimer, F. Kotz, T. M. Nargang, B. E. Rapp: "Suspended Liquid Subtractive Lithography: One-step generation of 3D channel geometries in viscous curable polymer matrices", Nature Scientific Reports 7, 7387, 2017 | Link

F. Ritter, J. Hedrich, M. Deck, F. Ludwig, D. Shakirov, B. E. Rapp, K. Länge: "Polymer structures on surface acoustic wave biosensors", Procedia Technology 27, 35-36, 2017 | Link

U. Stahl, A.Voigt, M. Dirschka, N. Barié, C. Richter, A. Waldbaur, F. J. Gruhl, B. E. Rapp, M. Rapp, K. Länge: "Long-Term Stability of Polymer-Coated Surface Transverse Wave Sensors for the Detection of Organic Solvent Vapors", Sensors, 274, 560-564, 2017 | Link

F. Kotz, K. Arnold, W. Bauer, D. Schild, N. Keller, K. Sachsenheimer, T. M. Nargang, C. Richter, D. Helmer, B. E. Rapp: "Three-dimensional Printing of Transparent Fused Silica Glass", Nature, 544, 337-339, 2017 | Link | Video | Media Coverage

C. Richter, F. Kotz, N. Keller, T. M. Nargang, K. Sachsenheimer, D. Helmer, B. E. Rapp: “An Analytical Solution to Neumann-Type Mixed Boundary Poiseuille Microfluidic Flow in Rectangular Channel Cross-Sections (Slip/No-Slip) Including a Numerical Technique to Derive It”, Journal of Biomedical Science and Engineering, 10, 205-219, 2017 | Link

C. Richter, K. Sachsenheimer, N. Keller, T. M. Nargang, D. Helmer, F. Kotz, B. E. Rapp: "An individual addressable and latchable actuator array for microfluidic systems", Microfluid Nanofluid  20:130, 2016. | Link

T. M. Nargang, M. Runck, D. Helmer, B. E. Rapp: "Functionalization of paper using photobleaching: a fast and convenient method for creating paper-based assays with colorimetric and fluorescent readout", Engineering in Life Sciences, 2016 | Link

C. Richter, F. Kotz, S. Giselbrecht, D. Helmer, B. E. Rapp: "Numerics made easy: solving the Navier–Stokes equation for arbitrary channel cross-sections using Microsoft Excel", Biomedical Microdevices 18:52, 2016 | Link

N. Keller, T. M. Nargang, M. Runck, F. Kotz, A. Striegel, K. Sachsenheimer, D. Klemm, K. Länge, M. Worgull, C. Richter, D. Helmer, B. E. Rapp: "Tacky Cyclo Olefin Copolymer: A biocompatible bonding technique for the fabrication of microfluidic channels in COC", Lab Chip, 16, 1561-1564, 2016 | Link

F. Kotz, K. Plewa, W. Bauer, N. Schneider, N. Keller, T. Nargang, D. Helmer, K. Sachsenheimer, M. Schäfer, M. Worgull, C. Greiner, C. Richter, B. E. Rapp: “Liquid Glass: A Facile Soft Replication Method for Structuring Glass”, Advanced Materials, 28, 4646-4650, 2016 Media Coverage | Link

N. E. Steidle, T. Hahn, C. Bader, R. Ahrens, B. E. Rapp, A. E. Guber, K. Länge: Localized protein immobilization on microstructured polymeric surfaces for diagnostic applications, Microfluidics and Nanofluidics, 20 (2), 1-11, 2016 | Link

F. Katzenwadel, H. Wagner, B. E. Rapp, M. Franzreb: “Optimization of Enzyme Immobilization onto magnetic microparticles using 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) as Crosslinking Agent”, Analytical Methods, 7, 10291-10298, 2015 | Link

H. Ito, N. Kuss, B. E. Rapp, M. Ichikawa; T. Gutsmann, K. Brandenburg; J. Poeschl, M. Tanaka: “Quantification of the Influence of Endotoxins on the Mechanics of Adult and Neonatal Red Blood Cells”, Journal of Physical Chemistry, 119, 25, 7837-7845, 2015 | Link

M. Kavalenka, F. Vüllers, S. Lischker, C. Zeiger, A. Hopf, M. Röhrig, B. E. Rapp, M. Worgull, H. Hölscher: “Bioinspired air-retaining nanofur for drag reduction", ACS Applied Materials & Interfaces, 7, 20, 10651-10655, 2015 | Link

A. Mattern, A. Pomowski, C. Baricham, B. E. Rapp, K. Länge: "Acoustic Biosensors Coated with Phosphorylcholine Groups for Label-free Detection of Human C-reactive Protein in Serum", IEEE Sensors Journal, 15, 8, 4388-4392, 2015 | Link

D. Helmer, I. Rink, J. A. R. Dalton, K. Brahm, M. Jöst, T. M. Nargang, W. Blum, P. Wadhwani, G. Brenner-Weiss, B. E. Rapp, J. Giraldo, K. Schmitz: “Rational design of a peptide capture agent for CXCL8 based on a model of the CXCL8:CXCR1 complex”, RSC Advances, 5, 25657-25668, 2015 | Link

E. Wilhelm, K. Deshpande, F. Kotz, D. Schild, N. Keller, S. Heissler, K. Sachsenheimer, K. Länge, C. Neumann, B. E. Rapp: “Polysiloxane layers created by sol-gel and photochemistry: Ideal surfaces for rapid, low-cost and high-strength bonding of epoxy components to polydimethylsiloxane”, Lab Chip, 15, 1772-1782, 2015 | Link

J. Bruchmann, K. Sachsenheimer, B. E. Rapp, T. Schwartz: “Multi-channel microfluidic biosensor platform applied for online monitoring and screening of biofilm formation and activity”, PLOS ONE, 10, 2, 2015 | Link

T. M. Nargang, L. Brockmann, P. Nikolov, D. Schild, D. Helmer, N. Keller, K. Sachsenheimer, E. Wilhelm, L. Pires, M. Dirschka, A. Kolew, M. Worgull, S. Giselbrecht, C. Neumann, B. E. Rapp: “Liquid polystyrene: a room-temperature photocurable soft lithography compatible pour-and-cure-type polystyrene”, Lab Chip (special issue “Emerging Investigators"), 14, 2698-2708, 2014 | Link

B. Waterkotte, F. Bally, P. M. Nikolov, A. Waldbaur, B. E. Rapp, R. Truckenmüller, J. Lahann, K. Schmitz, S. Giselbrecht: “Biofunctional Micropatterning of Thermoformed 3D Substrates”, Advanced Functional Materials, 24, 4, 442-450, 2014 | Link

E. Wilhelm, C. Neumann, T. Duttenhofer, L. Pires, B. E. Rapp: “Connecting microfluidic chips using a chemically inert, reversible, multichannel Chip-to-World-Interface”, Lab Chip, 13, 22, 4343-4351, 2013 | Link

E. Wilhelm, C. Neumann, K. Sachsenheimer, T. Schmitt, K. Länge, B. E. Rapp: “Rapid bonding of polydimethylsiloxane to stereolithographically manufactured epoxy components using a photogenerated intermediary layer”, Lab Chip, 13, 2268, 2013 | Link

A. Waldbaur, J. Kittelmann, C. Radtke, J. Hubbuch, B. E. Rapp: “Microfluidics on Liquid Handling Stations (µF-on-LHS): An Industry Compatible Chip Interface between Microfluidics and Automated Liquid Handling Stations”, Lab Chip, 13, 2337 – 2343, 2013 | Link

L. Pires, K. Sachsenheimer, T. Kleintschek, T. Schwartz, B. E. Rapp: “Online monitoring of biofilm growth and activity using a combined multi-channel impedimetric and amperometric sensor”, Biosensors and Bioelectronics, 47, 15, 157-163, 2013 | Link

A. Waldbaur, P. Hettich, B. Carneiro, B. E. Rapp: “Computer Aided Microfluidics (CAMF) - From Digital 3D-CAD Models to Physical Structures within a Day”, Microfluidics and Nanofluidics, 15, 625-635, 2013 | Link

C. Neumann, A. Voigt, L. Pires, B. E. Rapp: “Design and characterization of a platform for thermal actuation of up to 588 microfluidic valves”, Microfluidics and Nanofluidics, 14, 1-2, 177-186, 2012 | Link

A. Waldbaur, B. Waterkotte, K. Schmitz, B. E. Rapp: “Maskless projection lithography for the fast and flexible generation of grayscale protein patterns”, Small, 8, 10, 1570-1578, 2012 | Link

B. E. Rapp, A. Voigt, M. Dirschka, K. Länge: “Deposition of ultrathin parylene C films in the range of 18 nm to 142 nm: controlling the layer thickness and assessing the closeness of the deposited films”, Thin Solid Films, 520, 4884 – 4888, 2012 | Link

B. E. Rapp, B. Schickling, J. Prokop, V. Piotter, M. Rapp, K. Länge: "Design and integration of a generic disposable array-compatible sensor housing into an integrated disposable indirect microfluidic flow injection analysis system", Biomed. Microdevices, 13, 909-922, 2011 | Link

M. Worgull, A. Kolew, M. Heilig, M. Schneider, H. Dinglreiter, B. E. Rapp: "Hot embossing of high performance polymers", Microsyst. Technol., 17, 585-592, 2011 | Link

F. J. Gruhl, B. E. Rapp, M. Rapp, K. Länge: "Biosensor packaging - adaptation of the surface modification procedure", Procedia Engineering, 5, 363-366, 2010 | Link

C. Hannig, M. Dirschka, K. Länge, S. Neumaier, B. E. Rapp: "Synthesis and application of photo curable perfluoropolyethers as new material for microfluidics", Procedia Engineering, 5, 866-869, 2010 | Link

B. E. Rapp, M. Schneider, M. Worgull: "Hot punching on an 8 inch substrate as an alternative technology to produce holes on a large scale", Microsyst. Technol., 16, 1201-1206, 2010 | Link

B. E. Rapp, L. Carneiro, K. Länge, M. Rapp: "An indirect microfluidic flow injection analysis (FIA) system allowing diffusion free pumping of liquids by using tetradecane as intermediary liquid", Lab Chip, 9, 354-356, 2009 | Link

K. Länge, B. E. Rapp, M. Rapp: "Surface acoustic wave biosensors: a review", Analytical Bioanalytical Chemistry, 391, 1509-1519, 2008 | Link

D. Avramov, K. Länge, S. Rupp, B. E. Rapp, M. Rapp, "Polymer coating behaviour of Rayleigh-SAW resonators with gold electrode structure for gas sensor applications", IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control, 54, 157-166, 2007 | Link

Reviews

F. Kotz, P. Risch, D. Helmer, B. E. Rapp: “High-performance materials for 3D printing in chemical synthesis applications”, Advanced Materials (invited), 2019 |Link|

E. Wilhelm, C. Richter, B. E. Rapp: "Phase Change Materials in Microactuators: Basics, Applications and Perspectives", Sens. Act. A, 271, 303-347, 2018 | Link

F. Katzenwadel, M. Franzreb, B. E. Rapp: “Synthetic enzyme supercomplexes: co-immobilization of enzyme cascades”, Analytical Methods, 7, 18, 7924-7924, 2015 | Link

R. Meyer, S. Giselbrecht, B. E. Rapp, M. Hirtz, C. M. Niemeyer: “Advances in DNA-Directed Immobilization”, Opinion in Chemical Biology, 18, 8-15, 2014 | Link

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S. Giselbrecht, B. E. Rapp, C. M. Niemeyer: "The Chemistry of Cyborgs – Interfacing Technical Devices with Organisms", Angewandte Chemie, 52, 52, 13942–13957, 2013 | Link

S. Giselbrecht, B. E. Rapp, C. M. Niemeyer: "Chemie der Cyborgs – zur Verknüpfung technischer Systeme mit Lebewesen", Angewandte Chemie, 125, 52 14190-14206, 2013 | Link

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A. Waldbaur, H. Rapp, K. Länge, B. E. Rapp: "Let there be chip – towards rapid prototyping of microfluidic devices: one-step manufacturing processes", Analytical Methods, 3, 2681-2716, 2011 | Link

B. E. Rapp, F. J. Gruhl, K. Länge: "Biosensors with label-free detection designed for diagnostic applications", Analytical Bioanalytical Chemistry, 398, 2403-2412, 2010 | Link

Books and Book chapters

F. Kotz, D. Helmer, B. E. Rapp: “3D Printing of Transparent Glasses”, book chapter within "3D Printing of Optical Components", 169-184, Springer, 2020 |Link

F. Kotz, D. Helmer, B. E. Rapp: “Emerging Technologies and Materials for High-Resolution 3D Printing of Microfluidic Chips”, book chapter within "Advances in Biochemical Engineering/Biotechnology", Springer Nature, 2020 |Link

B. E. Rapp: "Electrochemical Methods for Biomass and Biocorrosion Monitoring", book chapter within "Encyclopedia of Interfacial Chemistry: Surface Science and Electrochemistry", Elsevier, 2018 | Link

B. E. Rapp: "Microfluidics: Mechanics, Modeling and Mathematics", 830 pages, Elsevier Scientific Publishing, ISBN 9781455731411, 12/2016 | Link

C. Neumann, B. E. Rapp: “Fluidic platforms and components of Lab-on-Chip devices”, book chapter within “Lab-on-a-Chip and Micro Total Analysis Systems – A Practical Guide” – edited by Jaime Castillo-León and Winnie Svendsen, Springer Publishing, ISBN 978-3-319-08686-6, 2015 | Link

F. J. Gruhl, B. E. Rapp, K. Länge: “Biosensors for Diagnostic Application”, book chapter within "Molecular Diagnostics", Advance in Biochemical Engineering / Biotechnology, Springer, 133, 115-148, 2013 | Link

B. E. Rapp: “Entwicklung eines Biosensorarray-Systems auf der Basis von akustischen Oberflächenwellensensoren mit integrierter einwegtauglicher Mikrofluidik (Development of a surface acoustic wave based biosensor array with integrated disposable microfluidics)”, Universitätsverlag Karlsruhe, Karlsruhe, ISBN 978-3-86644-318-1, 2009 | Link

Conference Contributions

Markus Mader, Leonhard Hambitzer, Holger Becker, Frederik Kotz-Helmer, Bastian E. Rapp: "High-throughput manufacturing of transparent fused silica glass by injection molding and extrusion", talk, SPIE Photonics West, San Francisco, USA, 2022

Markus Mader, Frederik Kotz-Helmer, Bastian E. Rapp: "Spritzguss von transparentem mikrostrukturiertem Quarzglas", talk, MikroSystemTechnik Kongress 2021, Ludwigsburg, Germany, 2021

K. Sachsenheimer, F. Mayoussi, A. Goralczyk, F. Kotz, D. Helmer and B. E. Rapp , Impedimetric Sensor for Salvinia Layer Detection on Fluoropor-coated Electrodes under Shear Stress, SPIE BiOS, 2021, Link

F. Mayoussi, E. H. Doeven, D. Helmer, B. E. Rapp, Membrane-based fluorinated microfluidic device for water-oil separation, SPIE BiOS, 2021

Markus Mader, Frederik Kotz, Bastian E. Rapp: "Towards high-throughput polymer replication of transparent fused silica glass", talk, SPIE Photonics West, San Francisco, USA, 2021

F. Kotz, P. Risch, M. Thiel, A. Quick, D. Helmer, B. E. Rapp: “Sacrificial Template Replication: Fabrication of arbitrary 3D microfluidic channels in transparent fused silica glass”, talk, SPIE Photonics West, San Francisco, USA, 2020

F. Kotz, L. Kneißl, P. Risch, B. E. Rapp: “Rapid prototyping of alumina-based microfluidic reactors”, talk, SPIE Photonics West, San Francisco, USA, 2020

M Luitz, P Risch, A Kick, M Reichel, D Helmer, F Kotz, BE Rapp

“Facile integration of electronics in glass microfluidic devices for electrochemical synthesis and analysis”, talk, SPIE Photonics West, San Francisco, USA, 2020

A Kick, D Helmer, F Kotz, B Rapp:“Generation of multi-level microstructures using a wavelength-selective photoresist and mask-less grayscale lithography”, talk, SPIE Photonics West, San Francisco, USA, 2020

F. Kotz, A. Striegel, N. Schneider, M. Worgull, B. E. Rapp: „High-throughput thermal replication of transparent fused silica glass”, talk, SPIE Photonics West, San Francisco, 2019.

T. M. Nargang, R. Dierkes, J. Bruchmann, N. Keller, K. Sachsenheimer, F. Kotz, D. Helmer, B. E. Rapp: „Structuring unbreakable and autoclavable hydrophobic barriers in paper via direct printing and mask-based photolithography”, talk, SPIE Photonics West, San Francisco, 2019.

D. Helmer, F. Kotz, B. E. Rapp: „Suspended liquid subtractive lithography: printing three dimensional channels directly into uncured polymeric matrices”, talk, SPIE Photonics West, San Francisco, 2019.

P. Risch, F. Kotz, D. Helmer, B. E. Rapp: „3D printing of highly fluorinated methacrylates for the rapid prototyping of transparent and chemically-resistant microfluidic devices”, talk, SPIE Photonics West, San Francisco, 2019.

M. Schmid, F. Kotz, P. Risch, D. Wußler, B. E. Rapp: „Wavelength-selective negative photoresist for photolithography suitable for generating microstructures with up to three distinct height levels per exposure”, talk, SPIE Photonics West, San Francisco, 2019.

M. Langenhorst, D. Ritzer, F. Kotz, P. Risch, I. Hossain, S. Dottermusch, A. Roslizar, R. Schmager, B. S: Richards, B. E. Rapp, U. W. Paetzold: „Advanced optical microstructures embedded in transparent encapsulation glass for photovoltaics”, talk, SPIE Photonics West, San Francisco, 2019.

F. Kotz, A. Striegel, N. Schneider, M. Worgull, D. Helmer, B. E. Rapp: „High-throughput structuring of fused silica glass“; talk, MNE, Kopenhagen, 2018.

K. Sachsenheimer, P. Risch, F. Kotz, C. Richter, B. E. Rapp, "Self-powered microfluidic sensing platform based on integrated microfluidic battery", poster, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Kaohsiung, Taiwan, 2018.

S. Schmidt, J. Bruchmann, C. Richter, M. Schüßler, R. Jakoby, T. Schwartz, B. E. Rapp: "A microfluidic approach for characterizing biofilm growth by microwave-based electrical impedance spectroscopy", poster, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Kaohsiung, Taiwan, 2018.

M. Langer, K. Sachsenheimer, T. Nargang, B. E. Rapp: "A fast fibrinogen targeted electrochemical assay for emergency room settings", poster, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Kaohsiung, Taiwan, 2018.

P. Risch, F. Kotz, D. Helmer, B. E. Rapp: "3D printing of highly fluorinated methacrylates for the fabrication of transparent and chemically resistant microfluidic devices", poster, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Kaohsiung, Taiwan, 2018.

P. Risch, F. Kotz, D. Helmer, B. E. Rapp: "3D printing of microfluidic glass reactors", poster, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Kaohsiung, Taiwan, 2018.

F. Kotz, A. Striegel, N. Schneider, P. Risch, M. Worgull, D. Helmer, B. E. Rapp: "High-throughput polymer molding of transparent fused silica microfluidic chips", poster, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Kaohsiung, Taiwan, 2018.

A. Striegel, S. Sharma, F. Kotz, B. E. Rapp, M. Schneider, D. Mager, J. G. Korvink, M. Worgull: „High-temperature micro/nano replication utilising lithographically patterned carbon tools“; MNE, Kopenhagen, Denmark, 2018

F. Kotz, P. Risch, K. Arnold, D. Helmer, B. E. Rapp: “Next generation 3D printing - The emergence of enabling materials”, talk, SPIE Defence and Security, Berlin, Germany, 2018| Link

D. Helmer: "Suspended Liquid Subtractive Lithography - Fabrication of three-dimensional microchannels by the immersion of "liquid threads"", talk, Microfluidics in the Upper Rhine Valley, IS2M Mulhouse 2018.

B. E. Rapp: "Next Generation 3D Printing - The emergence of enabling materials", talk, Microfluidics in the Upper Rhine Valley, IS2M Mulhouse 2018.

F. Kotz, D. Helmer, B. E. Rapp: "Additive manufacturing of microfluidic glass chips", talk, SPIE Photonics West, San Francisco, USA, 2018| Link

T. Nargang, F. Kotz, B. E. Rapp: "Structuring unbreakable hydrophobic barriers in paper", talk, SPIE Photonics West, San Francisco, USA, 2018| Link

D. Helmer, A. Voigt, S. Wagner, N. Keller, K. Sachsenheimer, F. Kotz, T. M. Nargang, B. E. Rapp: "Additive manufacturing of microfluidic glass chips", talk, SPIE Photonics West, San Francisco, USA, 2018

D. Helmer, A. Voigt, B. E. Rapp: "Suspended Liquid Subtractive Lithography (SLSL) – 3D printing of microfluidic structures directly into PDMS", 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Savannah, USA, 2017

F. Kotz, P. Risch, B. E. Rapp: “Rapid prototyping of microfluidic chips in polymethylmethacrylate (PMMA)”, talk, Mikrosystemtechnik Kongress (MST), München, Germany, 2017

F. Kotz, D. Helmer, B. E. Rapp: "3D printing of microfluidic devices in highly fluorinated perfluoropolyethers (PFPE)", poster, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Savannah, USA, 2017

S. Eckes, T. M. Nargang, B. E. Rapp, K. Schmitz: "Light-induced Chemokine Patterning of Surfaces", poster, 2nd European Chemokine and Cell Migration Conference", Cardiff, England, 2017

C. Richter, N. Kirschner, M. Worgull, B. E. Rapp: "Fast and cheap fabrication of molding tools for polymer replication", talk, SPIE Photonics West, San Francisco, USA, 2017| Link

 

T. M. Nargang, F. Kotz, N. Keller, D. Helmer, B. E. Rapp: “Rapid structuring of proteins on filter paper using lithography”, talk, SPIE Photonics West, San Francisco, USA, 2017| Link

F. Kotz, K. Arnold, B. E. Rapp: "Three-dimensional Printing of Transparent Fused Silica Microfluidic Chips", talk, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Savannah, USA, 2017

F. Gruhl, B. E. Rapp, K. Länge, A. Voigt, M. Rapp: "Surface Acoustic Wave (SAW) biosensors and their integration with microfluidics towards a flexible array based biosensor system", 3rd World congress on Digital Olfaction, Tokyo, Japan, 2016

D. Helmer, A. Voigt, S. Wagner, B. E. Rapp: "Rapid printing in PDMS – fused deposition modeling (FDM) meets microfluidics", talk, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Dublin, Ireland, 2016

K. Sachsenheimer, J. Bruchmann, T. Schwartz, B. E. Rapp: "Integrated peristaltic pump for probing a biofilm online monitoring system", poster, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Dublin, Ireland, 2016

F. Ritter, J. Hedrich, M. Deck, F. Ludwig, D. Shakirov, B .E  Rapp, K. Länge: “Polymer structures on surface acoustic wave biosensors”, poster, Biosensors, Gothenburg, Schweden, 2016

J. Bruchmann, K. Sachenheimer, T. Schwartz, B. E. Rapp: “Novel microfluidic system for online monitoring of biofilm dynamics by electrical impedance spectroscopy and amperometry”, talk, SPIE Photonics West, San Francisco, USA, 2016| Link

N. Keller, T. M. Nargang, B. E. Rapp: “Tacky COC: a solvent bonding technique for fabrication of microfluidic systems”, talk, SPIE Photonics West, San Francisco, USA, 2016| Link

C. Richter, K. Sachsenheimer, B. E. Rapp: “A latchable thermally activated phase change actuator for microfluidic systems”, talk, SPIE Photonics West, San Francisco, USA, 2016| Link

F. Kotz, K. Arnold, B. E. Rapp: “Rapid manufacturing of microfluidic chips in glass”, poster, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Dublin, Ireland, 2016

D. Helmer, N. Keller, B. E. Rapp: “Photolithographic structuring of highly fluorinated polymers for the fabrication of microfluidic chips”, talk, 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Gyeongju, Korea, 2015

F. Kotz, K. Plewa, C. Richter, B. E. Rapp: “Rapid prototyping of microfluidic chips in glass using a soft-lithography-compatible manufacturing process”, poster, 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Gyeongju, Korea, 2015

T. M. Nargang, E. Wilhelm, F. Kotz, D. Helmer, B. E. Rapp: “UV-light based structuring of unbreakable hydrophobic barriers on commonly used papers”, poster, 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Gyeongju, Korea, 2015

F. Kotz, C. Richter, B. E. Rapp: "’Liquid PMMA’: rapid prototyping of microfluidic structures in polymethylmethacrylate (PMMA) via direct lithography", poster, 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Gyeongju, Korea, 2015

D. Helmer, N. Keller, B. E. Rapp: “Reversibly Photoswitchable Hydrophilic/Hydrophobic Surfaces”, talk, ECOSS, Barcelona, Spain, 2015

J. Bruchmann, K. Sachsenheimer, B. E. Rapp, T. Schwartz: “Real-time biofilm monitoring in a multichannel online platform“, talk, Eurobiofilms, Brno, Czech Republic, 2015

C. Neumann, E. Wilhelm, A. Voigt, B. E. Rapp: “A latchable thermally activated phase change actuator and optimization of its response behavior”, poster, 18th International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers), Anchorage, USA, 2015

E. Wilhelm, T. M. Nargang, B. Waterkotte, B. E. Rapp: “Protein assay structured on paper by using lithography”, talk, SPIE Photonics West, San Francisco, USA, 2015| Link

F. Kotz, K. Plewa, W. Bauer, T. Hanemann, A. Waldbaur, E. Wilhelm, C. Neumann, B. E. Rapp: “Rapid prototyping of glass microfluidic chips”, talk, SPIE Photonics West, San Francisco, USA, 2015| Link

F. Kotz, C. Richter, B. E. Rapp: “A new rapid prototyping method for the fabrication of microfluidic chips in glass”, poster, Gordon Research Conference, Mount Snow, USA, 2015

F. Kotz, N. Keller, T.M. Nargang, K. Sachsenheimer, M. Dirschka, D. Helmer, C. Neumann, Bastian E. Rapp: “Computer aided microfluidics (CAMF): from 3D model to physical structures in less than a day”, talk, Euroanalysis, Bordeaux, France, 2015

E. Wilhelm, C. Neumann, K. Sachsenheimer, K. Länge, B. E. Rapp: “UV-light structured silanization for selective bonding and fabrication of paper-based microfluidic channels”, poster, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), San Antonio, USA, 2014

C. Neumann, E. Wilhelm, A. Voigt, B. E. Rapp: “A bistable microfluidic phase change actuator and optimization of its response times”, poster, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), San Antonio, USA, 2014

E. Wilhelm, T. Schwarz, G. Jaworek, A. Voigt, C. Neumann, B. E. Rapp: “Bistable, tubular phase change actuators for a large scale microfluidic membrane actuator platform”, poster, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), San Antonio, USA, 2014

L. Pires, N. Braunegger, G. Davidson, C. Neumann, B. E. Rapp: “Novel electrochemical biosensor surface modification method based on photobleaching”, poster, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), San Antonio, USA, 2014

T. M. Nargang, L. Brockmann, P. Nikolov, D. Schild, D. Helmer, N. Keller, M. Dirschka, A. Kolew, M. Worgull, S. Giselbrecht, C. Neumann, B. E. Rapp: “‘Liquid polystyrene’: a photocurable liquid polystyrene prepolymer as new material for microfluidic prototyping”, poster, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), San Antonio, USA, 2014

J. Bruchmann, K. Sachsenheimer, T. Kleintschek, T. Schwartz, B. E. Rapp: “Novel microfluidic biosensor for online monitoring of biofilm formation by EIS and amperometry”, poster, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), San Antonio, USA, 2014

B. Mall, K. Sachsenheimer, C. Neumann, J. Stölting, B. E. Rapp: “A low cost portable microfluidic electrochemical sensor for detection of arsenic in drinking water”, poster, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), San Antonio, USA, 2014

E. Wilhelm, T. Schwarz, G. Jaworek, A. Voigt, B. E. Rapp: “Towards displaying graphics on a cheap, large scale Braille display”, talk, 14th International Conference on Computers Helping People with Special Needs, Paris, France, 2014

E. Wilhelm, C. Neumann, T. Duttenhofer, L. Pires, B. E. Rapp: “A chemically inert, multichannel chip-to-world interface to connect microfluidic chips”, talk, SPIE Photonics West, San Francisco, USA, 2014| Link

E. Wilhelm, C. Neumann, K. Sachsenheimer, K. Länge, B. E. Rapp: “Rapid bonding of polydimethylsiloxane (PDMS) to various stereolithographically (STL) structurable epoxy resins using photochemically cross-linked intermediary siloxane layers”, talk, SPIE Photonics West, San Francisco, USA, 2014| Link

J. Kittelmann, C. Radtke, A. Waldbaur, C. Neumann, J. Hubbuch, B. E. Rapp: “Microfluidics on liquid handling stations (µF-on-LHS): a new industry-compatible microfluidic platform”, talk, SPIE Photonics West, San Francisco, USA, 2014| Link

J. Bruchmann, K. Sachsenheimer, B. E. Rapp, T. Schwartz: “Novel microfluidic biosensor for online monitoring of biofilm formation”, talk, DGHM/VAAM Microbiology and Infection, Dresden, 2014

J. Bruchmann, K. Sachsenheimer, T. Kleintschek, B. E. Rapp, T. Schwartz: “Novel microfluidic biosensor for online monitoring of biofilm formation”, talk, Biofilms6, Vienna, Austria, 2014

F. Gruhl, B. E. Rapp, K. Länge, A. Voigt, M. Rapp: “Surface Acoustic Wave (SAW) Biosensors and their Integration with Microfluidics towards a Flexible Array Based Biosensor System”, talk, Acoustic Sensors in Analytical and Biophysical Studies, Acoustic Sensors Meeting, Crete, 2013

E. Wilhelm, T. Schwarz, G. Jaworek, A. Voigt, B. E. Rapp: “A refreshable Braille-Display based on a microfluidic actuation principle”, poster, Gordon Research Conference: Physics & Chemistry of Microfluidics, Lucca, Italy, 2013

L. Pires, N. Braunegger, G. Davidson, B. E. Rapp: “Sensor Platform for High-Throughput Detection of Post-Translational Modifications (PTM) in Cellular Signalling Pathways”, poster, Gordon Research Conference: Physics & Chemistry of Microfluidics, Lucca, Italy, 2013

B. Waterkotte, A. Waldbaur, B. E. Rapp: “Creating protein patterns with light by means of maskless projection lithography”, poster, Functional Genomics & Proteomics, Frankfurt a. M., Germany, 2013

A. Waldbaur, B. Waterkotte, J. Leuthold, K. Schmitz, B. E. Rapp: “Rapid biochemical functionalization of technical surfaces by means of a photobleaching-based maskless projection lithography process”, talk, SPIE Photonics West, San Francisco, USA, 2013| Link

J. Bruchmann, T. Kleintschek, K. Sachsenheimer, L. Pires, T. Schwartz, B. E. Rapp: “Novel microfluidic multichannel biosensor for online monitoring of biofilm formation and activity via electrochemical impedance spectroscopy and amperometry”, poster, Eurobiofilms, Ghent, Belgium, 2013

A. Waldbaur, B. Carneiro, P. Hettich, B. E. Rapp: “Computer Aided Microfluidics: Rapid Generation of Structures from 3D Digital Data by means of Maskless Projection Lithography”, talk, IEEE EMBS Micro and Nanotechnology in Medicine Conference, Ka’anapali, USA, 2012

T. Kleintschek, K. Sachsenheimer, L. Pires, T. Schwartz, B. E. Rapp: “Monitoring of biofilm growth and activity using a scalable microfluidic electrochemical biosensor”, poster, 6th ASM Conference on Biofilms, Orlando, USA, 2012

K. Sachsenheimer, L. Pires, T. Kleintschek, T. Schwartz, B. E. Rapp: “Monitoring biofilm growth and activity using a scalable multichannel electrochemical biosensor”, poster, 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Okinawa, Japan, 2012

A. Waldbaur, B. Carneiro, P. Hettich, B. E. Rapp: “Computer Aided Microfluidics (CAMF) – high-resolution projection lithography for the rapid creation of large-scale microfluidic structures”, poster, 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Okinawa, Japan, 2012

L. Pires, A. Heckel, K. Sachsenheimer, B. E. Rapp: “Multichannel impedimetric biosensor platform for label-free affinity assays using electrically conductive functional polymers”, poster, 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Okinawa, Japan, 2012

T. Kleintschek, K. Sachsenheimer, H.-G. Lemaire, U. Obst, B. E. Rapp, T. Schwartz: “How do novel fungal components contribute to biofilm removal”, talk, BIOFILMS 5, Paris, France, 2012

A. Waldbaur, M. Dirschka, K. Länge, B. E. Rapp: “Rapid prototyping of microfluidic structures from UV curable PTFE-like polymers – creating structures in direct lithography and casting”, poster, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Seattle, USA, 2011

K. Sachsenheimer, L. Pires, M. Adamek, T. Schwartz, B. E. Rapp: “Monitoring biofilm growth using a scalable multichannel impedimetric biosensor”, poster, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Seattle, USA, 2011

C. Neumann, A. Voigt and B. E. Rapp: “A large scale thermal microfluidic valve platform”, poster, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Seattle, USA, 2011

C. Hannig, D. Schild, M. Dirschka, K. Länge, B. E. Rapp: “PTFE-like/PDMS hybrids: synthesis of photocurable, highly chemically resistant polymers and their applications in microfluidics”, poster, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Seattle, USA, 2011

M. Adamek, K. Sachsenheimer, T. Schwartz, B. E. Rapp: “Impedimetric sensor cell for monitoring biofilm growth”, talk, Eurobiofilms, Copenhagen, Denmark, 2011

C. Neumann, A. Voigt, B. E. Rapp: “A large scale microfluidic thermal valve platform”, poster, Gordon Research Conference on Microfluidics, Physics & Chemistry, Boston, USA, 2011

C. Hannig, J. Bolle, K. Länge, M. Dirschka, B. E. Rapp: “PDMS and beyond – New ways to synthesis highly fluorinated polymers for use as resist or bulk material in microfluidics”, poster, Gordon Research Conference on Microfluidics, Physics & Chemistry, Boston, USA, 2011

B. E. Rapp, T. Duttenhofer, K. Länge: “20/100/400 channel chemically inert, reversible parallel microfluidic connector as generic chip-to-world interface”, poster, 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), Groningen, Netherlands, 2010

B. E. Rapp, K. Länge, M. Rapp, V. Saile: “Connecting Micro to Macro Fluidics: New Concept for a Disposable Indirect Microfluidic Flow Injection Analysis (FIA) System”, talk, Pittcon, Orlando, USA, 2010

A. Günther, B. E. Rapp: “Design of a fully automated assembly unit for integration of surface acoustic wave sensors into polymer housings for biomedical applications”, talk, Design, Test, Integration & Packaging (DTIP) of MEMS/MOEMS, Seville, Spain, 2010

B. E. Rapp, M. Worgull: “Combining indirect microfluidic systems with polymer components manufactured from photocurable perfluoropolyethers”, talk, Design, Test, Integration & Packaging (DTIP) of MEMS/MOEMS, Seville, Spain, 2010

B. E. Rapp, M. Rapp, K. Länge: “An indirect diffusion free microfluidic flow injection analysis (FIA) system as fluidic platform for biosensor systems as demonstrated with an 8-fold surface acoustic wave biosensor array system”, talk, ICONN, Sydney, Australia, 2010

F. J. Gruhl, B. E. Rapp, M. Rapp, K. Länge: “Oberflächenmodifikation von SAW (Surface Acoustic Wave) Biosensorchips für biomedizinische Anwendungen”, poster, 9. Dresdner Sensor-Symposium, Dresden, Germany, 2009

B. E. Rapp, K. Länge, M. Rapp: “Ein indirektes einwegtaugliches diffusionsfreies mikrofluidisches Fließinjektionsanalyse-System als Plattform für die Biotechnologie”, poster, 9. Dresdner Sensor-Symposium, Dresden, Germany, 2009

B. E. Rapp: “Microfluidic Flow Injection Analysis (FIA) System allowing Diffusion Free and Indirect Pumping of Liquids by Using Tetradecane as Intermediary Liquid”, poster, Gordon Research Conference on Microfluidics, Physics & Chemistry, Lucca, Italy, 2009

B. E. Rapp, F. J. Gruhl, K. Länge, M. Rapp: “Surface acoustic wave (SAW) biosensor system with an indirect microfluidic flow injection analysis system”, poster, IEEE Transducers, Denver, USA, 2009

B. E. Rapp, M. Schneider, M. Worgull: "Hot punching on an 8 inch substrate as an alternative technology to produced holes on a large scale", talk, Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP), Rome, Italy, 136-139, 2009

F. J. Gruhl, B. E. Rapp, M. Rapp, K. Länge: "Surface Acoustic Wave (SAW) Biosensor Chip System - a Promising Alternative for Biomedical Applications", poster, Micro-and Nanosystems in Medicine, Active Implants, Biosensors, Munich, Germany, 2009

B. E. Rapp, F. J. Gruhl, K. Länge, M. Rapp: "Speeding up sensor response times by modifying the geometry of the fluidic channel of a disposable array compatible sensor housing for surface acoustic wave biosensors", poster, Micro-and Nanosystems in Medicine, Active Implants, Biosensors, Munich, Germany, IFMBE Proceedings, 25, 69-72, 2009

F. J. Gruhl, B. E. Rapp, M. Rapp, K. Länge: “SAW (surface acoustic wave) Biosensorchip-Array für biomedizinische Anwendungen”, talk, 6. Deutsches Biosensor Symposium, Freiburg, Germany, 2009

B. E. Rapp, F. Gruhl, M. Rapp, K. Länge: “Warum soll Bioanalytik teuer sein? Ein kostengünstiges 8-Kanal Biosensorsystem mit einwegtauglicher Mikrofluidik”, talk, Biotechnica, Hannover, Germany, 2008

B. E. Rapp, M. Rapp, K. Länge: “Surface Acoustic Wave (SAW) Biosensors for Biomolecular Applications”, talk, Workshop Molecular Interactions, Freie Universität, Berlin, Germany, 2008

B. E. Rapp, K. Länge, M. Rapp: “An array compatible polymer housing for a Love wave surface acoustic wave (SAW) biosensor allowing the elimination of conductivity sensitivities of SAW resonators”, talk, International Meeting on Chemical Sensors IMCS, Columbus, USA, 2008

B. E. Rapp, K. Länge, M. Rapp: “Microfluidic flow injection analysis (FIA) system which allows indirect fluid handling by using tetradecane as intermediary liquid”, talk, International Meeting on Chemical Sensors IMCS, Columbus, USA, 2008

B. E. Rapp, L. Carneiro, K. Länge, M. Rapp: "Integration of a Surface Acoustic Wave (SAW) Biosensor into a Microfluidic Flow Injection Analysis (FIA) System", talk, Sensoren und Messsysteme 2008, Ludwigsburg, Germany; VDI Berichte, 53-56, 2008

B. E. Rapp, K. Länge, M. Rapp, A. Guber: “Surface acoustic wave biosensors for biomedical applications”, talk, 41. Jahrestagung der Deutschen Gesellschaft für Biomedizinische Technik (DGBMT) im VDE, Aachen, Germany, 2007

B. E. Rapp, M. Worgull, M. Heckele, A. Guber, D. Herrmann: “Mikro-Heißstanzen - Erzeugung von Durchlochstrukturen in ebenen Kunststoffsubstraten”, talk, Mikrosystemtechnik Kongress, Freiburg, Germany, 2005

B. E. Rapp, D. Herrmann, A. Guber, A. Welle, D. Schild, A. Jacob, M. Dauber, J. Hoheisel: “Mikrotiterplatte mit integrierter funktionalisierter Filterstruktur”, poster, Mikrosystemtechnik Kongress, Freiburg, Germany, 2005

Patents

B. E. Rapp, C. Neumann, E. Wilhelm, A. Voigt: "Bistable actuator, actuator arrangement, method for actuation and use", US9689408B2, 2017.

B. E. Rapp, D. Helmer, A. Voigt: "Verfahren und Vorrichtung zur Erzeugung einer dreidimensionalen Struktur in einer Matrix", DE102016219192, 2016 | Link.

B. E. Rapp, D. Helmer, A. Voigt: "Method and apparatus for generating a three-dimensional structure in a matrix“, EP3305495A1, 2016 | Link.

B. E. Rapp, F. Kotz: "Transparentes Quarzglas für die additive Fertigung", DE102016012003, 2016 | Link.

B. E. Rapp, F. Kotz: "Composition and process for producing a molded article of high-purity, transparent quartz glass by means of additive manufacturing”, WO2018065093, 2016 | Link.

B. E. Rapp, D. Helmer, C. Richter, N. Keller: "Hochfluorierte nanostrukturierte Polymerschäume zur Herstellung superabweisender Oberflächen", DE102016012001A1, 2016 | Link.

B. E. Rapp, D. Helmer, C. Richter, N. Keller: “Highly fluorinated nanostructured polymer foams for producing super-repellent surface”, WO2018065094A1, 2016 | Link.

B. E. Rapp, A. Schumacher: “Method and arrangement for generating or depositing a stream of fluid segments and use thereof”, US8651129B2, 2014 | Link

B. E. Rapp, L. Carneiro, A. Voigt: “Device for controlling the flow of fluids through microfluidic channels”, US8480974B2, 2013 | Link

B. E. Rapp, C. Neumann, E. Wilhelm, A. Voigt: "Bistabiler Aktor, Aktoranordnung, Verfahren zum Aktuieren und Verwendung”, DE102012005992B3, 2013 | Link

B. E. Rapp, A. Schumacher, "Vorrichtung und Verfahren zur Erzeugung oder zur Ablage eines Fluidstroms aus Fluidsegmenten und ihre Verwendung", DE102010047384B4, 2012 | Link

B. E. Rapp, T. Duttenhofer: “Verfahren zum reversiblen, parallelen Schließen einer Vielzahl von fluidischen Zuleitungen mit einem mikrofluidischen System”, DE102009053285B4, 2012 | Link

B. E. Rapp, L. Carneiro, A. Voigt: "Vorrichtung zur Erzeugung einer mikrofluidischen Kanalstruktur in einer Kammer, Verfahren zu ihrer Herstellung und ihre Verwendung", DE102009035291B4, 2011 | Link

B. E. Rapp, L. Carneiro, K. Länge, M. Rapp, "Vorrichtung und Verfahren zur Zuführung eines Flüssigkeitsstroms aus mindestens zwei Flüssigkeitsabschnitten in eine Messzelle", DE102007032951B4, 2007 | Link

B. E. Rapp, M. Worgull, M. Heckele, "Verfahren zur Herstellung von Durchbrüchen in thermoplastischen Komponenten", DE102005025247B3, 2007 | Link

Miscellaneous

D. Helmer, B. E. Rapp: "Superabweisende Oberflächen - Die Entwicklung eines superhydrophoben Werkstoffs", GIT Labor-Fachzeitschrift, 2018 | Link

T. M. Nargang, B. E. Rapp: "Chemical Modification of Paper for Analytical Devices", HEALTH Europa 5, Paneuropean Network, 2018. | Link

D. Helmer, B. E. Rapp: "Healthcare Material Platforms", HEALTH 2, Paneuropean Network, 2017. The NeptunLab is features on the cover page of the issue | Link | Cover

B. Waterkotte, A. Waldbaur, J. Kashef, B. E. Rapp, K. Schmitz: "Mit Proteinen Bilder malen –Strukturierungsmethoden für Proteine auf Oberflächen", GIT Labor-Fachzeitschrift - GIT Verlag, Wiley, 2012| Link